Do you have a peanut allergy?

About this study

This clinical study is testing an investigational treatment for peanut allergy. The study aims to understand how safe the treatment is and how the immune system responds to it in adults with a confirmed peanut allergy.

The treatment being studied is not approved and is only available through this research study. It has not been given to people before, which is why the study includes close medical monitoring and detailed safety assessments. The study involves specialist doctors and trained clinical staff, and all procedures are conducted in a controlled clinical environment.

This study has been reviewed and approved by an independent Human Research Ethics Committee.

Who can take part

You may be eligible if you:

• Are 18 to 55 years old
• Have a doctor-diagnosed peanut allergy
• Have had allergy testing (such as a skin prick test or blood test) confirming peanut allergy
• Are able to attend multiple clinic visits over several months
• Are willing to undergo medically supervised allergy testing as part of the study
• Have access to an in-date adrenaline (epinephrine) auto-injector

You cannot take part if you

• Have had a recent severe or life-threatening allergic reaction
• Have a history of serious reactions to mRNA vaccines
• Have had myocarditis or pericarditis
• Are currently pregnant or breastfeeding
• Are unable to safely stop certain allergy medications before testing
• Are unable to commit to the required clinic visits and follow-up

Final eligibility is determined by the study doctor after screening assessments.

What’s involved

• An initial screening period to confirm eligibility
• A medically supervised peanut food challenge to assess your allergy level
• Up to three intramuscular injections of the investigational study treatment over time
• Short periods of in-clinic monitoring, including one overnight stay after the first dose
• Regular follow-up visits, blood tests and health checks
• A second supervised peanut food challenge later in the study
• Ongoing safety monitoring throughout the study

The total study duration is approximately 5 to 9 months, depending on the dosing schedule. You can withdraw from the study at any time without giving a reason.

Safety and your rights

All procedures take place in a controlled clinical environment at accredited research facilities in Perth, the Gold Coast and Brisbane, under the supervision of specialist doctors and trained clinical staff. You’ll receive full written study information before consenting, and choosing not to take part won’t affect your usual medical care.

Check my eligibility